Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

A poliovirus (PV) mutant (termed GG), which is incapable of producing 3AB, VPg, and 3CD proteins due to a defective cleavage site between the 3B and 3C proteins, replicated, producing 3BC-linked RNA rather than the VPg-linked RNA produced by the wild type (WT). GG PV RNA is quasi-infectious. The yie...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Oh, Hyung Suk, Pathak, Harsh B., Goodfellow, Ian G., Arnold, Jamie J., Cameron, Craig E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738245/
https://ncbi.nlm.nih.gov/pubmed/19587035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02076-08
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados