Upregulation of Interleukin 7 Receptor Alpha and Programmed Death 1 Marks an Epitope-Specific CD8(+) T-Cell Response That Disappears following Primary Epstein-Barr Virus Infection

In immunocompetent individuals, the stability of the herpesvirus-host balance limits opportunities to study the disappearance of a virus-specific CD8(+) T-cell response. However, we noticed that in HLA-A*0201-positive infectious mononucleosis (IM) patients undergoing primary Epstein-Barr virus (EBV)...

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Detalhes bibliográficos
Main Authors: Sauce, Delphine, Larsen, Martin, Abbott, Rachel J. M., Hislop, Andrew D., Leese, Alison M., Khan, Naeem, Papagno, Laura, Freeman, Gordon J., Rickinson, Alan B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738242/
https://ncbi.nlm.nih.gov/pubmed/19605492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00141-09
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