Nucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic Center

Highly pathogenic influenza virus strains currently in circulation pose a significant risk of a global pandemic. Following the reported crystal structure of the endonuclease domain from the avian influenza virus polymerase PA subunit, here we report the results of a systematic X-ray crystallographic...

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Detalhes bibliográficos
Main Authors: Zhao, Cong, Lou, Zhiyong, Guo, Yu, Ma, Ming, Chen, Yutao, Liang, Shuaiyi, Zhang, Liang, Chen, Shoudeng, Li, Xuemei, Liu, Yingfang, Bartlam, Mark, Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738217/
https://ncbi.nlm.nih.gov/pubmed/19587036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00911-09
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