Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production

Intracranial (i.c.) infection of mice with lymphocytic choriomeningitis virus (LCMV) results in anorexic weight loss, mediated by T cells and gamma interferon (IFN-γ). Here, we assessed the role of CD4(+) T cells and IFN-γ on immune cell recruitment and proinflammatory cytokine/chemokine production...

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Detalhes bibliográficos
Main Authors: Lin, Adora A., Tripathi, Pulak K., Sholl, Allyson, Jordan, Michael B., Hildeman, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738201/
https://ncbi.nlm.nih.gov/pubmed/19515766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02477-08
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