Effect of Hemagglutinin-Neuraminidase Inhibitors BCX 2798 and BCX 2855 on Growth and Pathogenicity of Sendai/Human Parainfluenza Type 3 Chimera Virus in Mice

Human parainfluenza virus type 3 (hPIV-3) is a major respiratory tract pathogen that affects young children, but no vaccines or antiviral drugs against it have yet been developed. We developed a mouse model to evaluate the efficacies of the novel parainfluenza virus hemagglutinin-neuraminidase (HN)...

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Detalhes bibliográficos
Main Authors: Watanabe, Makiko, Mishin, Vasiliy P., Brown, Scott A., Russell, Charles J., Boyd, Kelli, Babu, Y. Sudhakara, Taylor, Garry, Xiong, Xiaoping, Yan, Xiaowei, Portner, Allen, Alymova, Irina V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737897/
https://ncbi.nlm.nih.gov/pubmed/19564364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00220-09
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