Vancomycin and Daptomycin Pharmacodynamics Differ against a Site-Directed Staphylococcus epidermidis Mutant Displaying the Small-Colony-Variant Phenotype

Catheter-related bloodstream infections due to slow-growing Staphylococcus epidermidis small-colony variants (SCVs) are extremely difficult to treat. Daptomycin and vancomycin pharmacodynamics were evaluated against a site-directed hemB mutant of S. epidermidis displaying the SCV phenotype and compa...

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Detalhes bibliográficos
Main Authors: Wu, Marina, von Eiff, Christof, Al Laham, Nahed, Tsuji, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737885/
https://ncbi.nlm.nih.gov/pubmed/19564372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01597-08
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