Target Analysis of the Experimental Measles Therapeutic AS-136A

No effective therapeutic is currently in place for improved case management of severe measles or the rapid control of outbreaks. Through high-throughput screening, we recently identified a novel small-molecule class that potently blocks activity of the measles virus (MeV) RNA-dependent RNA polymeras...

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Bibliographic Details
Main Authors: Yoon, Jeong-Joong, Krumm, Stefanie A., Ndungu, J. Maina, Hoffman, Vanessa, Bankamp, Bettina, Rota, Paul A., Sun, Aiming, Snyder, James P., Plemper, Richard K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737882/
https://ncbi.nlm.nih.gov/pubmed/19528268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00503-09
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