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A Novel Tryptophanyl-tRNA Synthetase Gene Confers High-Level Resistance to Indolmycin
Indolmycin, a potential antibacterial drug, competitively inhibits bacterial tryptophanyl-tRNA synthetases. An effort to identify indolmycin resistance genes led to the discovery of a gene encoding an indolmycin-resistant isoform of tryptophanyl-tRNA synthetase. Overexpression of this gene in an ind...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology (ASM)
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737876/ https://ncbi.nlm.nih.gov/pubmed/19546369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00723-09 |
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