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Evaluation of Target Specificity of Antibacterial Agents Using Staphylococcus aureus ddlA Mutants and d-Cycloserine in a Silkworm Infection Model

The availability of a silkworm larva infection model to evaluate the therapeutic effectiveness of antibiotics was examined. The 50% effective doses (ED(50)) of d-cycloserine against the Staphylococcus aureus ddlA mutant-mediated killing of larvae were remarkably lower than those against the parental...

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Detalhes bibliográficos
Main Authors: Kurokawa, Kenji, Hamamoto, Hiroshi, Matsuo, Miki, Nishida, Satoshi, Yamane, Noriko, Lee, Bok Luel, Murakami, Kazuhisa, Maki, Hideki, Sekimizu, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737873/
https://ncbi.nlm.nih.gov/pubmed/19546371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00200-09
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