Genetic Analysis of Peptidoglycan Biosynthesis in Mycobacteria: Characterization of a ddlA Mutant of Mycobacterium smegmatis

A temperature-sensitive mutant of Mycobacterium smegmatis was characterized that contains a mutation in ddlA, the gene encoding d-alanine:d-alanine ligase. Enzymatic assays using recombinant proteins and d-cycloserine susceptibility indicate that the A365V mutation in the SMEG35 DdlA protein causes...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Belanger, Aimee E., Porter, Joelle C., Hatfull, Graham F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Enzymes and Proteins
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.23.6854-6856.2000
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