Genetic Analysis of Peptidoglycan Biosynthesis in Mycobacteria: Characterization of a ddlA Mutant of Mycobacterium smegmatis

A temperature-sensitive mutant of Mycobacterium smegmatis was characterized that contains a mutation in ddlA, the gene encoding d-alanine:d-alanine ligase. Enzymatic assays using recombinant proteins and d-cycloserine susceptibility indicate that the A365V mutation in the SMEG35 DdlA protein causes...

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Bibliographic Details
Main Authors: Belanger, Aimee E., Porter, Joelle C., Hatfull, Graham F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Enzymes and Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC111435/
https://ncbi.nlm.nih.gov/pubmed/11073937
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