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Efficacy of Aerosol MP-376, a Levofloxacin Inhalation Solution, in Models of Mouse Lung Infection Due to Pseudomonas aeruginosa

Progressive respiratory failure due to Pseudomonas aeruginosa is the leading cause of morbidity and mortality in patients with cystic fibrosis. The pulmonary delivery of antimicrobial agents provides high concentrations of drug directly to the site of infection and attains pharmacokinetic-pharmacody...

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Detalhes bibliográficos
Main Authors: Sabet, Mojgan, Miller, Courtney E., Nolan, Thomas G., Senekeo-Effenberger, Kathy, Dudley, Michael N., Griffith, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737871/
https://ncbi.nlm.nih.gov/pubmed/19528273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00268-09
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