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The Diarylquinoline R207910 Is Bactericidal against Mycobacterium leprae in Mice at Low Dose and Administered Intermittently

The diarylquinoline R207910 is profoundly bactericidal in a murine model of tuberculosis. Previously, R207910 was also found to be bactericidal for Mycobacterium leprae-infected mice during lag phase. Herein we evaluate the bactericidal efficacy of R207910 (1 to 120 mg/kg of body weight) when admini...

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Detalhes bibliográficos
Main Authors: Gelber, Robert, Andries, Koen, Paredes, Rose Maria D., Andaya, Cora Evelyn S., Burgos, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737847/
https://ncbi.nlm.nih.gov/pubmed/19596891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00722-09
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