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CYP2C9*8 is prevalent among African–Americans: implications for pharmacogenetic dosing

AIMS: Although the frequencies of pharmacogenetic variants differ among racial groups, most pharmacogenetic algorithms for genotype-guided warfarin dosing only include two CYP2C9 alleles (*2 and *3) and a single VKORC1 allele (g.-1639G>A or g.1173C>T) commonly found among Caucasians. Therefore...

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Detalhes bibliográficos
Main Authors: Scott, Stuart A, Jaremko, Malgorzata, Lubitz, Steven A, Kornreich, Ruth, Halperin, Jonathan L, Desnick, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737687/
https://ncbi.nlm.nih.gov/pubmed/19663669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.09.71
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