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An interdomain RNA binding site on the hepadnaviral polymerase that is essential for reverse transcription
The T3 motif on the duck hepatitis B virus reverse transcriptase (P) is proposed to be a binding site essential for viral replication, but its ligand and roles in DNA synthesis are unknown. Here, we found that T3 is needed for P to bind the viral RNA, the first step in DNA synthesis. A second motif,...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737686/ https://ncbi.nlm.nih.gov/pubmed/19467554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.04.023 |
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