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An interdomain RNA binding site on the hepadnaviral polymerase that is essential for reverse transcription

The T3 motif on the duck hepatitis B virus reverse transcriptase (P) is proposed to be a binding site essential for viral replication, but its ligand and roles in DNA synthesis are unknown. Here, we found that T3 is needed for P to bind the viral RNA, the first step in DNA synthesis. A second motif,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Badtke, Matthew P., Khan, Irfan, Cao, Feng, Hu, Jianming, Tavis, John E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737686/
https://ncbi.nlm.nih.gov/pubmed/19467554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.04.023
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