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Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect

BACKGROUND: The unique metabolism of tumors was described many years ago by Otto Warburg, who identified tumor cells with increased glycolysis and decreased mitochondrial activity. However, “aerobic glycolysis” generates fewer ATP per glucose molecule than mitochondrial oxidative phosphorylation, so...

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Hlavní autoři: Chen, Yijun, Cairns, Rob, Papandreou, Ioanna, Koong, Albert, Denko, Nicholas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737639/
https://ncbi.nlm.nih.gov/pubmed/19753307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007033
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