Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment

BACKGROUND: Frailty in older adults, defined as a constellation of signs and symptoms, is associated with abnormal levels in individual physiological systems. We tested the hypothesis that it is the critical mass of physiological systems abnormal that is associated with frailty, over and above the s...

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Autors principals: Fried, Linda P., Xue, Qian-Li, Cappola, Anne R., Ferrucci, Luigi, Chaves, Paulo, Varadhan, Ravi, Guralnik, Jack M., Leng, Sean X., Semba, Richard D., Walston, Jeremy D., Blaum, Caroline S., Bandeen-Roche, Karen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
Journal of Gerontology: Medical Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737590/
https://ncbi.nlm.nih.gov/pubmed/19567825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glp076
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