Nonlinear Multisystem Physiological Dysregulation Associated With Frailty in Older Women: Implications for Etiology and Treatment

BACKGROUND: Frailty in older adults, defined as a constellation of signs and symptoms, is associated with abnormal levels in individual physiological systems. We tested the hypothesis that it is the critical mass of physiological systems abnormal that is associated with frailty, over and above the s...

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Detalhes bibliográficos
Main Authors: Fried, Linda P., Xue, Qian-Li, Cappola, Anne R., Ferrucci, Luigi, Chaves, Paulo, Varadhan, Ravi, Guralnik, Jack M., Leng, Sean X., Semba, Richard D., Walston, Jeremy D., Blaum, Caroline S., Bandeen-Roche, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Journal of Gerontology: Medical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737590/
https://ncbi.nlm.nih.gov/pubmed/19567825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glp076
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