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The 26-Amino Acid ß-Motif of the Pit-1ß Transcription Factor Is a Dominant and Independent Repressor Domain
The POU-homeodomain transcription factor Pit-1 governs the pituitary cell-specific expression of Pit-1, GH, prolactin (PRL), and TSHß genes. Alternative splicing generates Pit-1ß, which contains a 26-amino acid ß-domain inserted at amino acid 48, in the middle of the Pit-1 transcription activation d...
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Autors principals: | , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
The Endocrine Society
2009
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737555/ https://ncbi.nlm.nih.gov/pubmed/19556346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0137 |
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