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The 26-Amino Acid ß-Motif of the Pit-1ß Transcription Factor Is a Dominant and Independent Repressor Domain

The POU-homeodomain transcription factor Pit-1 governs the pituitary cell-specific expression of Pit-1, GH, prolactin (PRL), and TSHß genes. Alternative splicing generates Pit-1ß, which contains a 26-amino acid ß-domain inserted at amino acid 48, in the middle of the Pit-1 transcription activation d...

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Bibliografische gegevens
Hoofdauteurs: Jonsen, Matthew D., Duval, Dawn L., Gutierrez-Hartmann, Arthur
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Endocrine Society 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737555/
https://ncbi.nlm.nih.gov/pubmed/19556346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0137
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