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Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
Store-operated Ca(2+) entry through calcium release–activated calcium channels is the chief mechanism for increasing intracellular Ca(2+) in immune cells. Here we show that mouse T cells and fibroblasts lacking the calcium sensor STIM1 had severely impaired store-operated Ca(2+) influx, whereas defi...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737533/ https://ncbi.nlm.nih.gov/pubmed/18327260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1574 |
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