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Donepezil Treatment Restores the Ability of Estradiol to Enhance Cognitive Performance in Aged Rats: Evidence for the Cholinergic Basis of the Critical Period Hypothesis

Recent studies suggest that the ability of estradiol to enhance cognitive performance diminishes with age and/or time following loss of ovarian function. We hypothesize that this is due, in part, to a decrease in basal forebrain cholinergic function. This study tested whether donepezil, a cholineste...

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Detalhes bibliográficos
Main Authors: Gibbs, R.B., Mauk, R., Nelson, D., Johnson, D.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737520/
https://ncbi.nlm.nih.gov/pubmed/19303882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2009.03.003
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