Upregulation of Glt1 Attenuates Cue-Induced Reinstatement of Cocaine-Seeking Behavior in Rats

Relapse to cocaine-seeking behavior depends on increased glutamate transmission in key regions of the mesocorticolimbic motive circuit, including prefrontal cortex (PFC) and nucleus accumbens (NAcc). Because GLT1 is responsible for the uptake of ≥90% of extracellular glutamate, we tested the hypothe...

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Main Authors: Sari, Youssef, Smith, Kathryn D., Ali, Pir K., Rebec, George V.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
Assuntos:
Brief Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737464/
https://ncbi.nlm.nih.gov/pubmed/19625514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1746-09.2009
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