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Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states : regulation by gender and adiposity

BACKGROUND: Recombinant human leptin (r-metHuLeptin) has demonstrated efficacy in improving hormonal and metabolic parameters in leptin-deficient states, and it has been suggested that leptin replacement may reverse metabolic adaptations during weight loss iterventions. Pharmacokinetics of subcutane...

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Autori principali: Chan, Jean L., Wong, Shekman L., Mantzoros, Christos S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737404/
https://ncbi.nlm.nih.gov/pubmed/18840030
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