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DNA hybridization assays using metal-enhanced fluorescence

We describe a new approach to DNA hybridization assays using metal-enhanced fluorescence. Thiolated oligonucleotides were bound to silver particles on a glass substrate. Addition of a complementary fluorescein-labeled oligonucleotide resulted in a dramatic time-dependent 12-fold increase in fluoresc...

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Bibliografiska uppgifter
Huvudupphovsmän: Malicka, Joanna, Gryczynski, Ignacy, Lakowicz, Joseph R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737384/
https://ncbi.nlm.nih.gov/pubmed/12788090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-291X(03)00935-5
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