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DNA hybridization assays using metal-enhanced fluorescence
We describe a new approach to DNA hybridization assays using metal-enhanced fluorescence. Thiolated oligonucleotides were bound to silver particles on a glass substrate. Addition of a complementary fluorescein-labeled oligonucleotide resulted in a dramatic time-dependent 12-fold increase in fluoresc...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737384/ https://ncbi.nlm.nih.gov/pubmed/12788090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-291X(03)00935-5 |
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