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Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours

BACKGROUND: Hypoxia, which is commonly observed in areas of primary tumours and of metastases, influences response to treatment. However, its characterisation has so far mainly been restricted to the ex vivo analysis of tumour sections using monoclonal antibodies specific to carbonic anhydrase IX (C...

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Detalhes bibliográficos
Main Authors: Ahlskog, J K J, Schliemann, C, Mårlind, J, Qureshi, U, Ammar, A, Pedley, R B, Neri, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736829/
https://ncbi.nlm.nih.gov/pubmed/19623173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605200
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