Common genetic variation in six lipid- and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke

OBJECTIVE: Genetic polymorphisms are associated with lipid-lowering response to statins, but generalizeability to disease endpoints is unclear. The association between 82 common single nucleotide polymorphisms (SNPs) in 6 lipid- or statin-related genes (ABCB1, CETP, HMGCR, LDLR, LIPC, NOS3) and inci...

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Hlavní autoři: Hindorff, Lucia A., Lemaitre, Rozenn N., Smith, Nicholas L., Bis, Joshua C., Marciante, Kristin D., Rice, Kenneth M., Lumley, Thomas, Enquobahrie, Daniel A., Li, Guo, Heckbert, Susan R., Psaty, Bruce M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736793/
https://ncbi.nlm.nih.gov/pubmed/18622260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283033528
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