Common genetic variation in six lipid- and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke

OBJECTIVE: Genetic polymorphisms are associated with lipid-lowering response to statins, but generalizeability to disease endpoints is unclear. The association between 82 common single nucleotide polymorphisms (SNPs) in 6 lipid- or statin-related genes (ABCB1, CETP, HMGCR, LDLR, LIPC, NOS3) and inci...

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書誌詳細
主要な著者: Hindorff, Lucia A., Lemaitre, Rozenn N., Smith, Nicholas L., Bis, Joshua C., Marciante, Kristin D., Rice, Kenneth M., Lumley, Thomas, Enquobahrie, Daniel A., Li, Guo, Heckbert, Susan R., Psaty, Bruce M.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736793/
https://ncbi.nlm.nih.gov/pubmed/18622260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283033528
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