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Enzyme-Sensitive MR Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques

BACKGROUND: Inflammation undermines the stability of atherosclerotic plaques, rendering them susceptible to acute rupture, the cataclysmic event that underlies clinical expression of this disease. Myeloperoxidase (MPO) is a central inflammatory enzyme secreted by activated macrophages, and is involv...

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Bibliografische gegevens
Hoofdauteurs: Ronald, John A., Chen, John W., Chen, Yuanxin, Hamilton, Amanda M., Rodriguez, Elisenda, Reynolds, Fred, Hegele, Robert A., Rogers, Kem A., Querol, Manel, Bogdanov, Alexei, Weissleder, Ralph, Rutt, Brian K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736635/
https://ncbi.nlm.nih.gov/pubmed/19652086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.813998
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