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A microwave assisted intramolecular-furan-Diels–Alder approach to 4-substituted indoles

The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels–Alder cycloaddition and an in situ double aromatization reaction.

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Bibliographische Detailangaben
Hauptverfasser: Petronijevic, Filip, Timmons, Cody, Cuzzupe, Anthony, Wipf, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736609/
https://ncbi.nlm.nih.gov/pubmed/19082013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b816989f
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