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An experimentally guided umbrella sampling protocol for biomolecules

We present a simple method for utilizing experimental data to improve the efficiency of numerical calculations of free energy profiles from molecular dynamics simulations. The method involves umbrella sampling simulations with restraining potentials based on a known approximate estimate of the free...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Mills, Maria, Andricioaei, Ioan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Institute of Physics 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736582/
https://ncbi.nlm.nih.gov/pubmed/19044944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.2976440
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