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Mapping accessible chromatin regions using Sono-Seq
Disruptions in local chromatin structure often indicate features of biological interest such as regulatory regions. We find that sonication of cross-linked chromatin, when combined with a size-selection step and massively parallel short-read sequencing, can be used as a method (Sono-Seq) to map loca...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736440/ https://ncbi.nlm.nih.gov/pubmed/19706456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905443106 |
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