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Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity

Glucose and glutamine are abundant nutrients required for cell growth, yet how cells sense and adapt to changes in their levels is not well understood. The MondoA transcription factor forms a heterocomplex with its obligate partner Mlx to regulate ≈75% of glucose-dependent transcription. By mediatin...

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Detalhes bibliográficos
Main Authors: Kaadige, Mohan R., Looper, Ryan E., Kamalanaadhan, Sadhaasivam, Ayer, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736411/
https://ncbi.nlm.nih.gov/pubmed/19706488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901221106
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