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Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation

G protein-coupled receptor kinases (GRKs) specifically phosphorylate activated G protein-coupled receptors. While the X-ray crystal structures of several GRKs have been solved, the mechanism of GRK interaction with GPCRs is currently unknown. To further characterize the role of the GRK2 amino termin...

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Hlavní autoři: Pao, Christina S., Barker, Breann L., Benovic, Jeffrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736393/
https://ncbi.nlm.nih.gov/pubmed/19715378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900408g
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