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Cross-Clade Neutralizing Antibodies Against HIV-1 Induced in Rabbits by Focusing the Immune Response on a Neutralizing Epitope

Studies were performed to induce cross-clade neutralizing antibodies (Abs) by testing various combinations of prime and boost constructs that focus the immune response on structurally conserved epitopes in the V3 loop of HIV-1 gp120. Rabbits were immunized with gp120 DNA containing a V3 loop charact...

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Bibliographische Detailangaben
Hauptverfasser: Zolla-Pazner, Susan, Cohen, Sandra, Pinter, Abraham, Krachmarov, Chavdar, Wrin, Terri, Wang, Shixia, Lu, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736369/
https://ncbi.nlm.nih.gov/pubmed/19632700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.05.039
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