Human Monoclonal Antibodies Specific for Conformation-Sensitive Epitopes of V3 Neutralize Human Immunodeficiency Virus Type 1 Primary Isolates from Various Clades

The epitopes of the V3 domain of the human immunodeficiency virus type 1 (HIV-1) gp120 glycoprotein have complex structures consisting of linear and conformational antigenic determinants. Anti-V3 antibodies (Abs) recognize both types of elements, but Abs which preferentially react to the conformatio...

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Detalhes bibliográficos
Main Authors: Gorny, Miroslaw K., Williams, Constance, Volsky, Barbara, Revesz, Kathy, Cohen, Sandra, Polonis, Victoria R., Honnen, William J., Kayman, Samuel C., Krachmarov, Chavdar, Pinter, Abraham, Zolla-Pazner, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136433/
https://ncbi.nlm.nih.gov/pubmed/12186887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9035-9045.2002
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