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A Catalytic Asymmetric Route to Carbapenems

[Image: see text] Efficient syntheses of N-acetyl thienamycin and epithienamycin A in readily deprotected form are reported where three contiguous stereocenters are established in a single catalytic asymmetric azetidinone-forming reaction. These examples are a template for synthesizing C5/C6 cis or...

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Autores principales: Bodner, Micah J., Phelan, Ryan M., Townsend, Craig A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736320/
https://ncbi.nlm.nih.gov/pubmed/19610642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol901269d
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