t(14;18)-negative Follicular Lymphomas Are Associated with a High Frequency of BCL6 Rearrangement at the Alternative Breakpoint Region

A frequent chromosomal translocation in mature B-cell non-Hodgkin lymphoma affects band 3q27 and results in deregulation of the B-cell lymphoma 6 (BCL6) gene. Two breakpoint clusters have been described thus far, the major breakpoint region (MBR) and an alternative breakpoint region (ABR) that is lo...

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Autores principales: Gu, Keni, Fu, Kai, Jain, Smrati, Liu, Zhongfen, Iqbal, Javeed, Li, Min, Sanger, Warren G, Weisenburger, Dennis D, Greiner, Timothy C, Aoun, Patricia, Dave, Bhavana J, Chan, Wing C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736319/
https://ncbi.nlm.nih.gov/pubmed/19465899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2009.81
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