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Inhibition of Rac by the GAP activity of Centralspindlin is Essential for Cytokinesis

During cytokinesis, the small GTPase RhoA orchestrates contractile ring assembly and constriction. RhoA signaling is controlled by the central spindle—a set of microtubule bundles that forms between the separating chromosomes. Centralspindlin, a protein complex consisting of the kinesin-6 ZEN-4, and...

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Autors principals: Canman, Julie C., Lewellyn, Lindsay, Laband, Kimberley, Smerdon, Stephen J., Desai, Arshad, Bowerman, Bruce, Oegema, Karen
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736296/
https://ncbi.nlm.nih.gov/pubmed/19056985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163086
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