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Inhibition of Rac by the GAP activity of Centralspindlin is Essential for Cytokinesis
During cytokinesis, the small GTPase RhoA orchestrates contractile ring assembly and constriction. RhoA signaling is controlled by the central spindle—a set of microtubule bundles that forms between the separating chromosomes. Centralspindlin, a protein complex consisting of the kinesin-6 ZEN-4, and...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736296/ https://ncbi.nlm.nih.gov/pubmed/19056985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163086 |
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