Llwytho...

Vβ Cluster Sequences Reduce the Frequency of Primary Vβ2 and Vβ14 Rearrangements

T cell receptor (TCR) β variable region exons are assembled from numerous gene segments in a highly ordered and regulated manner. To elucidate mechanisms and identify cis-acting elements that control Vβ rearrangement, we generated an endogenous TCRβ allele with only the Vβ2, Vβ4, and Vβ14 segments....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bassing, Craig H., Whitlow, Scott, Mostoslovasky, Raul, Yang, Katherine, Ranganath, Sheila, Alt, Frederick W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736105/
https://ncbi.nlm.nih.gov/pubmed/18792409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838347
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