A Thyroid Hormone Analog with Reduced Dependence on the Monocarboxylate Transporter 8 for Tissue Transport

Mutations of the thyroid hormone (TH) cell membrane transporter MCT8, on chromosome-X, produce severe mental and neurological impairment in men. We generated a Mct8-deficient mouse (Mct8KO) manifesting the human thyroid phenotype. Although these mice have no neurological manifestations, they have de...

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Hlavní autoři: Di Cosmo, Caterina, Liao, Xiao-Hui, Dumitrescu, Alexandra M., Weiss, Roy E., Refetoff, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736078/
https://ncbi.nlm.nih.gov/pubmed/19497976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0209
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