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Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis

Understanding the cellular mechanism(s) by which the oto- and nephrotoxic aminoglycoside antibiotics penetrate cells, and the precise intracellular distribution of these molecules, will enable identification of aminoglycoside-sensitive targets, and potential uptake blockers. Clones of two kidney cel...

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Detalhes bibliográficos
Main Authors: Myrdal, Sigrid E., Johnson, Katherine C., Steyger, Peter S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736065/
https://ncbi.nlm.nih.gov/pubmed/15925201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2005.02.002
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