Clinical Grade Ex Vivo-Expanded Human Natural Killer Cells Upregulate Activating Receptors and Death Receptor Ligands and Have Enhanced Cytolytic Activity against Tumor Cells

BACKGROUND: Cancer immunotherapy involving NK-cell infusions and administration of therapeutic agents modulating the susceptibility of tumors to NK-cell lysis has been recently proposed. Here we provide a method to expand highly cytotoxic clinical grade NK cells in vitro for adoptive transfer follow...

Full description

Saved in:
Bibliographic Details
Main Authors: Berg, Maria, Lundqvist, Andreas, McCoy, Philip, Samsel, Leigh, Fan, Yong, Tawab, Abdul, Childs, Richard
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736058/
https://ncbi.nlm.nih.gov/pubmed/19308771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14653240902807034
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items