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Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis

Homeobox (Hox) genes encode transcription factors that act as critical regulators of growth and differentiation during embryogenesis. While many studies have identified increased expression of Hox genes in tumors, much less is known about the mechanistic basis by which Hox genes facilitate tumor dev...

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Bibliografiske detaljer
Hovedforfatter: Radisky, Derek C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735897/
https://ncbi.nlm.nih.gov/pubmed/19726879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40555
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