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Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis

Homeobox (Hox) genes encode transcription factors that act as critical regulators of growth and differentiation during embryogenesis. While many studies have identified increased expression of Hox genes in tumors, much less is known about the mechanistic basis by which Hox genes facilitate tumor dev...

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Bibliografske podrobnosti
Glavni avtor: Radisky, Derek C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735897/
https://ncbi.nlm.nih.gov/pubmed/19726879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40555
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