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Molecular geometry of CsrA (RsmA) binding to RNA and its implications for regulated expression

The global regulatory protein CsrA binds to the 5′-untranslated leader of target transcripts and alters their translation and/or stability. CsrA is a symmetrical homodimer containing two identical RNA-binding surfaces. Gel shift assays with model RNA substrates now show that CsrA can bind simultaneo...

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Hlavní autoři: Mercante, Jeffrey, Edwards, Adrianne N., Dubey, Ashok K., Babitzke, Paul, Romeo, Tony
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735826/
https://ncbi.nlm.nih.gov/pubmed/19619561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.034
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