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Molecular geometry of CsrA (RsmA) binding to RNA and its implications for regulated expression
The global regulatory protein CsrA binds to the 5′-untranslated leader of target transcripts and alters their translation and/or stability. CsrA is a symmetrical homodimer containing two identical RNA-binding surfaces. Gel shift assays with model RNA substrates now show that CsrA can bind simultaneo...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735826/ https://ncbi.nlm.nih.gov/pubmed/19619561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.034 |
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