Synthetic Galectin-3 Inhibitor Increases Metastatic Cancer Cell Sensitivity to Taxol-Induced Apoptosis In Vitro and In Vivo

At present, there is no efficient curative therapy for cancer patients with advanced metastatic disease. Targeting of antiapoptotic molecules acting on the mitochondrial apoptosis pathway could potentially augment antimetastatic effect of cytotoxic drugs. Similarly to Bcl-2 family members, β-galacto...

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Autors principals: Glinsky, Vladislav V, Kiriakova, Galina, Glinskii, Olga V, Mossine, Valeri V, Mawhinney, Thomas P, Turk, James R, Glinskii, Anna B, Huxley, Virginia H, Price, Janet E, Glinsky, Gennadi V
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735801/
https://ncbi.nlm.nih.gov/pubmed/19724684
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